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DNA

Bio_160_Lecture3

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Inheritance and DNA Cellular Basis of Reproduction & Inheritance ? Chapter 8 The cell cycle multiplies cells and consists of two major phases Figure 8.5 ? The stages of cell division Figure 8.6 (Part 1) Figure 8.6 (Part 2) Cytokinesis differs for plant and animal cells Figure 8.7A The binding of growth factors to specific receptors on the plasma membrane is usually necessary for cell division. Control systemG1 S G2M G1 checkpoint Plasma membrane Growth factor Receptor protein Relay proteins Signal transduction pathway Figure 8.9B ? Cancer cells divide excessively to form masses of cells called tumors ?Malignant tumors can invade other tissues Tumor Glandular tissue A tumor grows from a single cancer cell. Cancer cells invade

Ch03_Bio PPT

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Inheritance and DNA Cellular Basis of Reproduction & Inheritance Chapter 8 The cell cycle multiplies cells and consists of two major phases Figure 8.5 The stages of cell division Figure 8.6 (Part 1) Figure 8.6 (Part 2) Cytokinesis differs for plant and animal cells Figure 8.7A The binding of growth factors to specific receptors on the plasma membrane is usually necessary for cell division. Control system G1 S G2 M G1 checkpoint Plasma membrane Growth factor Receptor protein Relay proteins Signal transduction pathway Figure 8.9B Cancer cells divide excessively to form masses of cells called tumors Malignant tumors can invade other tissues Tumor Glandular tissue A tumor grows from a single cancer cell. Cancer cells invade neighboring tissue.

AP Biology Chapter 16 Notes Campbell/Reece

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Chapter 16 The Molecular Basis of Inheritance Essay questions will be on Feulgen, Griffith experiement, Hershey and Chase, Chargoff, Watson and Crick, Tatum Beadle Experiment Overview: Your genetic material is contained in: 1. 46 chromsomes from mom and dad 2. Mitochondrial DNA from mom Nucleic acids - Unique from all other molecules in that they can direct their own replication. 16.1 DNA is the genetic material A. The Search for Genetic Material: Scientific Inquiry Initially, Genes were noted to be on chromosomes (b/c of work by Morgan an d Mendel) ? so people didn?t know if they were on the proteins or on the DNA. 1. Frederick Griffith (figure 16.2)? Showed evidence that DNA (not protein) can transform bacteria Background:

Structure of DNA

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Discovery of the Structure of DNA On the last day of February in 1953, according to James Watson, Francis Crick announced to the patrons of the Eagle Pub in Cambridge, ?We have discovered the secret of life? (Watson 115, 1980). As Brian Hayes, the author of ?The Invention of the Genetic Code? states, ?If life ever had a secret, the double helix of DNA was surely it? (1). However, it was not the work of these two men alone that led to the discovery of the power the lies within the double helix, but rather the work of many scientists that was carefully picked apart and pieced together by the two who received the most fame for the work.

Summary of Chapter 26

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Chapter 26 ? Phylogeny and the Tree of Life Overview: Investigating the Tree of Life Process of evolution ? the evolutionary mechanisms (from Unit 4) Pattern of Evolution ? observations of evolution?s products over time. (focus of this chapter) Phylogeny ? The evolutionary history of a species or group of species. Systematics - A discipline focues on classifying organisms and determining their evolutionary relationships. Systematics uses data from fossils to molecules and genes to infer evolutionary relationships. (figure 26.2) 26.1 Phylogenies show evolutionary relationships Taxonomy ? the scientific discipline of how organisms are named and classified. A. Binomial Nomeclature (Instituted by Linnaeus) Binomial: The two part format of the scientific name

Summary of Chapter 21

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AP Biology Chapter 21 Genomes and Their Evolution Overview ? Reading the Leaves form the Tree of Life Scientists are now able to compare different species by comparing their DNA We have sequenced the full DNA of many different species now By comparing, we can: study the set of genes that control group defining characteristics Learn about the long evolutionary history of shared ancient genes and their products (by looking at the genome of more different species such as bacteria, fungi, etcs and comparing to animals/humans.) Genomics: The study of whole sets of genes and their interactions. Bioinformatics: a new field ? the application of computational methods to the storage and analysis of biological data.

ps 2.3

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Practice Problems for Molecular Biology, Session 3: Transcription, Translation ? ? Question 1 ? ? Fill in the table: ? Transcription Translation Where does this process occur in a eukaryotic cell? ? ? What is the enzyme that carries out this process? ? ? What is the template that is read during this process? ? ? In what direction is the template read? ? ? What is the start signal/sequence for this process? ? ? What is the polymer that is formed? ? ? What monomer is used to form this polymer? ? ? What type of bond is formed between monomers? ? ? In what direction is the new polymer formed? ? ? What is the stop signal/sequence for this process? ? ?

exam 2

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Molecular Biology Unit Exam Question 1 Consider the following origin of replication that is found on a chromosome. The sequence of region 1 is shown below. Region 1: 5??CTGACTGACA?3? 3??GACTGACTGT?5? 3? 5? 5? 3? Region 1 top ? ori bottom ? a) Within Region 1, which strand will be the template for leading strand synthesis, the top or the bottom? b) If we assume that a lagging strand fragment is made from region 1, what will be its sequence? c) You examine DNA replication in an E. coli mutant, which has a partially defective DNA polymerase. In vitro experiments using the mutant DNA polymerase gives an error rate of 10-3, as compared to the expected error

Ps2 soln

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H Solutions for Practice Problems for Molecular Biology, Session 2: DNA Replication Question 1 ATP * * H a) Box the part that is added to a growing chain of nucleic acid. b) Star the atom(s) that can form a hydrogen bond with the complementary nitrogenous base. c) Circle the part of the molecule that decreases the stability of RNA as compared to DNA.

PS2

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Practice Problems for Molecular Biology, Session 2: DNA Replication Question 1 ATP ? a) Box the part that is added to a growing chain of nucleic acid. b) Star the atom(s) that can form a hydrogen bond with the complementary nitrogenous base. c) Circle the part of the molecule that decreases the stability of RNA as compared to DNA. d) Draw an arrow to the part of this molecule that you would modify to prevent further elongation. Indicate what change you would make next to the arrow drawn. Question 2 Consider the following origin of replication that is found on a chromosome. The sequence of region 1 is shown. Region 1: 5??CTGACTGACA?3?

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