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Lone pair

hybrization

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Worksheet ? Hybridization One model to explain bonding in molecules is called the valence bond theory. It is based on the concept of hybridized molecular orbitals. Atomic orbitals (s,p,d) are mathematically mixed to form molecular orbitals with defined shapes and energy levels. In organic chemistry, we need only look at the hybridization of the one 2s and three 2p orbitals containing the valence electrons of C,O and N. When four equivalent molecular orbitals are needed, all four atomic orbitals are mixed to give sp3 hybridization. When three equivalent molecular orbitals are needed, three of the atomic orbitals are mixed to give sp2 hybridization. In this case, one unhybridized p atomic orbital remains, with its shape and energy level

Organic Chemistry Lecture 19a

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Chapter 19 ? 2010, Prentice Hall Organic Chemistry, 7th Edition L. G. Wade, Jr. Amines Chapter 19 * Biologically Active Amines The alkaloids are an important group of biologically active amines, mostly synthesized by plants to protect them from being eaten by insects and other animals. Many drugs of addiction are classified as alkaloids. Chapter 19 * Biological Activity of Amines Dopamine is a neurotransmitter. Epinephrine is a bioregulator. Niacin, Vitamin B6, is an amine. Alkaloids: nicotine, morphine, cocaine Amino acids Chapter 19 Chapter 19 * Classes of Amines Primary (1?): Has one alkyl group bonded to the nitrogen (RNH2). Secondary (2?): Has two alkyl groups bonded to the nitrogen (R2NH). Tertiary (3?): Has three alkyl groups bonded to the nitrogen (R3N).
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