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AP Biology Chapter Outlines & Objectives
Campbell’s Biology,
7th Edition Created by: C. Massengale, Stuttgart School District Chapter Outline:
Chapter Objectives:
Relating Mendelian Inheritance to the Behavior of Chromosomes
1. Explain how the observations of cytologists
and geneticists provided the basis for the chromosome theory of inheritance.
2. Explain why Drosophila melanogaster is a good
experimental organism for genetic studies.
3. Explain why linked genes do not assort
independently.
4. Distinguish between parental and recombinant
phenotypes.
5. Explain how crossing over can unlink genes.
6. Explain how Sturtevant created linkage maps.
7. Define a map unit.
8. Explain why Mendel did not find linkage
between seed color and flower color, despite the fact that these genes are on
the same chromosome.
9. Explain how genetic maps are constructed for
genes located far apart on a chromosome.
10. Explain the effect of multiple crossovers between loci.
11. Explain what additional information cytogenetic maps
provide.
Sex Chromosomes
12. Describe how sex is genetically determined in humans and
explain the significance of the SRY gene.
13. Distinguish between linked genes and sex-linked genes.
14. Explain why sex-linked diseases are more common in human
males.
15. Describe the inheritance patterns and symptoms of color
blindness, Duchenne muscular dystrophy, and hemophilia.
16. Describe the process of X inactivation in female
mammals. Explain how this phenomenon produces the tortoiseshell coloration in
cats.
Errors and Exceptions in Chromosomal Inheritance
17. Explain how nondisjunction can lead to aneuploidy.
18. Define trisomy, triploidy, and polyploidy. Explain how
these major chromosomal changes occur and describe possible consequences.
19. Distinguish among deletions, duplications, inversions,
and translocations.
20. Describe the type of chromosomal alterations responsible
for the following human disorders: Down syndrome, Klinefelter syndrome, extra
Y, triple-X syndrome, Turner syndrome, cri du chat syndrome, and chronic
myelogenous leukemia.
21. Define genomic imprinting. Describe the evidence that
suggests that the Igf2 gene is maternally imprinted.
22. Explain why extranuclear genes are not inherited in a
Mendelian fashion.
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